
🩸 Menstrual Cycle (Periods, PMS, and PMDD)
1. Increased sensory sensitivity:
Autistic women often report heightened pain perception and sensory overload around their period — e.g., feeling cramps, smells, sounds, or textures more intensely.
2. Stronger emotional reactions:
Hormonal fluctuations can amplify autistic traits — many report more meltdowns, shutdowns, or emotional dysregulation during PMS or menstruation.
3. PMDD (Premenstrual Dysphoric Disorder):
Rates of PMDD (a severe form of PMS with mood disturbance) appear higher in autistic women, possibly because of how estrogen and progesterone fluctuations interact with autistic neurology and serotonin systems.
4. Communication barriers:
Some autistic women may struggle to recognize or communicate internal bodily changes (“alexithymia”), leading to delayed diagnosis or misunderstanding of symptoms.
🔥 Menopause and Perimenopause
1. Symptom intensity:
Studies (including emerging UK research) show autistic women report stronger menopausal symptoms, especially:
- Hot flashes and sleep disturbances
- Heightened anxiety and irritability
- Worsened sensory sensitivity
- Increased brain fog and fatigue
2. Autistic traits may intensify:
Many report that masking becomes harder and autistic traits re-emerge after years of suppression — some even seek or receive an autism diagnosis during menopause because the hormonal shifts make their traits more apparent.
3. Hormonal vulnerability:
Autistic women may have different hormone sensitivity or neuroendocrine regulation, making them more reactive to fluctuations in estrogen and progesterone. Estrogen influences serotonin, GABA, and dopamine — all key systems implicated in autism.
4. Lack of research and support:
Most menopause research excludes neurodivergent participants, so autistic women often feel misunderstood or dismissed by healthcare providers.
💡 In summary
| Aspect | Autistic Women | Neurotypical Women |
|---|---|---|
| PMS / PMDD | More intense mood and sensory symptoms | Milder, often more predictable |
| Pain sensitivity | Heightened | Typical range |
| Emotional regulation | More difficulty, especially during hormonal shifts | More stable |
| Menopause symptoms | Often stronger and longer lasting | Variable |
| Medical understanding | Often under-recognized | Better understood |
🧠 Why this matters
- Hormones directly affect neurotransmitters involved in autistic experience (e.g., serotonin, dopamine, GABA).
- The autonomic nervous system — already dysregulated in many autistic people — may overreact to hormonal stress.
- Sensory, emotional, and interoceptive sensitivities magnify both the physical and emotional impact of cycles.
🩺 Support strategies
- Track symptoms with a cycle or menopause app to spot hormonal triggers for sensory or emotional changes.
- Discuss PMDD, HRT (hormone replacement therapy), or alternative treatments with a GP familiar with neurodivergence.
- Practice sensory regulation (cooling packs, breathable fabrics, calming spaces).
- Consider autistic-friendly menopause resources, such as those by Autistic Women & Nonbinary Network (AWN) or Autistic Girls Network UK.

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